Goitrin

Definition

Goitrin is a hydrolysis product of glucosinolates, specifically the breakdown of certain isothiocyanates. It is part of the oxazolidine-2-thione family of glucosinolate products. See: Glucosinolates.

Health considerations

Goitrin has anti-thyroid effects; it interferes with the production of thyroid hormones such as thyroxine (T3).

Keep in mind

Longer cooking, particularly in water, reduces glucosinolate content and therefore goitrin content. Individuals with hypothyroidism should note the effects of goitrin.

May be found in

Cruciferous vegetables: cabbage, broccoli, cauliflower, brussels sprouts, kale

References

Human & Experimental Toxicology
National Product Reports

Alternative Spellings and Names

5-ethenyl-1,3-oxazolidine-2-thione, 5-vinyloxazolidine-2-thione